Tuesday, August 08, 2017
Moffitt: New Research Shows the Power of Radiomics to Improve Precision Medicine

In a collaborative project, researchers at the Moffitt Cancer Center and Dana-Farber Cancer Institute investigated the emerging field of radiomics has the potential to improve precision medicine by non-invasively assessing the molecular and clinical characteristics of lung tumors. ..

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Monday, July 17, 2017
Moffitt:Radiation Therapy Prior to Surgery Reduces the Risk of Secondary Tumors in Early-Stage Breast Cancer Patients

Moffitt Cancer Center researchers launched a first of its kind study comparing the long-term benefits of radiation therapy in women with breast cancer either before surgery (neoadjuvant) or after surgery (adjuvant).  ..

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Saturday, July 01, 2017
Moffitt Cancer Center Targets Tumors by Using More Precise Radiation Method

Clinicians at Moffitt Cancer Center are better able to aim radiation therapy directly at tumors, while avoiding surrounding tissues by using MRI-guidance. ..

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Wednesday, June 14, 2017
Experimental Drug Co-Developed by Moffitt Cancer Center Researcher Shows Promise

A collaboration between Saïd M. Sebti, Ph.D., chair of Moffitt Cancer Center’s Drug Discovery Department, and Michele Pagano, M.D., chair of the Department of Biochemistry and Molecular Pharmacology at New York University’s Langone Medical Center, found that the drug, geranylgeranyltransferase inhibitor GGTI-2418 suppresses a new defective PTEN cancer pathway discovered by Pagano’s group. ..

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Monday, May 29, 2017
Moffitt Researchers Demonstrate Mathematical Modeling Can Identify Ways to Limit Aggressive Tumor Cell Growth

Cancers can be viewed as complex dynamic systems because they have many interacting parts that can change over time and space. Perhaps the most well-known complex dynamic system is the weather and, similar to weather forecasting, researchers in the Integrated Mathematical Oncology Department at the Moffitt Cancer Center are using mathematical methods to account for many variables in the search for new ways to understand and control cancer.  ..

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Tuesday, March 28, 2017
New Study Identifies 12 New Genetic Variants Linked to Ovarian Cancer

There is new proof your genes may hold the key to whether or not you have a higher risk of developing cancer. Moffitt Cancer Center researchers took part in a major international study published in Nature Genetics that identified 12 new genetic variants associated with an increased risk of developing epithelial ovarian cancer, the most common and dangerous type of the disease.  ..

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Thursday, February 16, 2017
Mayo Clinic to test vaccine designed to provide immune response against early breast lesions

Keith Knutson, Ph.D., director of the Discovery and Translation Labs Cancer Research Program at Mayo Clinic’s campus in Florida, has received a $3.7 million grant from the U.S. Department of Defense to conduct a phase II clinical trial that will test a vaccine designed to establish lifelong immunity against development of these precancerous lesions. ..

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Thursday, January 12, 2017
Vaccine Shows Promising Results for Early-Stage Breast Cancer Patients

Immunotherapy is a fast growing area of cancer research. It involves developing therapies that use a patient’s own immune system to fight and kill cancer. Moffitt Cancer Center is working on a new vaccine that would help early-stage breast cancer patients who have HER2 positive disease. ..

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Wednesday, January 11, 2017
Moffitt Cancer Center Researchers Develop Novel Treatment to Prevent Graft-Versus-Host-Disease

Graft-versus-host-disease (GVHD) is the leading cause of non-relapse associated death in patients who receive stem cell transplants. In a new study published as the cover story in Science Translational Medicine, Moffitt Cancer Center researchers show that a novel treatment can effectively inhibit the development of GVHD in mice and maintain the infection- and tumor-fighting capabilities of the immune system.  ..

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Saturday, December 17, 2016
Moffitt Researchers Develop First Genomics-Driven Model for Personalized Radiation Therapy

Cancer therapeutics is currently in the era of precision medicine – personalized medicine for individual patients based on their tumor biology. Precision medicine is generally drug-based and little emphasis is placed on radiation therapy that is often assumed to be a “one-size-fits-all” treatment. Moffitt Cancer Center researchers have been instrumental is changing this assumption.  ..

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